BDBM31794 2-aminobenzimidazole deriv., 4::5-Chloro-1H-benzoimidazol-2-ylamine::5-chloro-1H-benzo[d]imidazol-2-amine::6-chloro-1H-benzimidazol-2-amine::6-chloro-1H-benzo[d]imidazol-2-amine::CHEMBL269158

SMILES Nc1nc2ccc(Cl)cc2[nH]1

InChI Key InChIKey=PDOCNPCPPLPXRV-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31794   

TargetBeta-secretase 1(Homo sapiens (Human))
Evotec

Curated by ChEMBL

LigandBDBM31794(2-aminobenzimidazole deriv., 4 | 5-Chloro-1H-benzo...)Copy SMILESCopy InChI

Affinity DataIC50:  7.31E+5nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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